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s-c-i-guy:

Scientists stimulate brown fat to burn more energy from food
The number of overweight persons is greatly increasing worldwide - and as a result is the risk of suffering a heart attack, stroke, diabetes or Alzheimer’s disease. For this reason, many people dream of an efficient method for losing weight. Scientists have now come one step closer to this goal. The scientists discovered a new way to stimulate brown fat and thus burn energy from food: The body’s own adenosine activates brown fat and “browns” white fat.
"Not all fat is equal," says Professor Alexander Pfeifer from the Institute of Pharmacology and Toxicology of the University Hospital Bonn. Humans have two different types of fat: undesirable white fat cells which form bothersome "love handles," for example, as well as brown fat cells, which act like a desirable heater to convert excess energy into heat. "If we are able to activate brown fat cells or to convert white fat cells into brown ones, it might be possible to simply melt excess fat away" reports the pharmacologist.
The group of Prof. Pfeifer together with an international team from Sweden, Denmark, Finland, as well as from the Helmholtz-Center Dresden-Rossendorf and the University of Düsseldorf now discovered a new signalling molecule capable of activating brown fat cells: adenosine. Adenosine is typically released during stress. Crucial for transmitting the adenosine signal is the adenosine receptor A2A.

Image: Brown fat cells under the microscope. Lipids are in red.
Credit: AG Alexander Pfeifer/UKB

read more

s-c-i-guy:

Scientists stimulate brown fat to burn more energy from food

The number of overweight persons is greatly increasing worldwide - and as a result is the risk of suffering a heart attack, stroke, diabetes or Alzheimer’s disease. For this reason, many people dream of an efficient method for losing weight. Scientists have now come one step closer to this goal. The scientists discovered a new way to stimulate brown fat and thus burn energy from food: The body’s own adenosine activates brown fat and “browns” white fat.

"Not all fat is equal," says Professor Alexander Pfeifer from the Institute of Pharmacology and Toxicology of the University Hospital Bonn. Humans have two different types of fat: undesirable white fat cells which form bothersome "love handles," for example, as well as brown fat cells, which act like a desirable heater to convert excess energy into heat. "If we are able to activate brown fat cells or to convert white fat cells into brown ones, it might be possible to simply melt excess fat away" reports the pharmacologist.

The group of Prof. Pfeifer together with an international team from Sweden, Denmark, Finland, as well as from the Helmholtz-Center Dresden-Rossendorf and the University of Düsseldorf now discovered a new signalling molecule capable of activating brown fat cells: adenosine. Adenosine is typically released during stress. Crucial for transmitting the adenosine signal is the adenosine receptor A2A.

Image: Brown fat cells under the microscope. Lipids are in red.

Credit: AG Alexander Pfeifer/UKB

read more